| Commercial name | Mediterranean Whitening |
| Application | Skin Care |
| Function | Illuminating • Depigmenting |
| Use level | 1-3% |
Actions
- High antioxidant power
- Depigmenting effect demonstrated in vitro by determining the inhibition of the tyrosinase enzyme
Suggested applications
- Anti-aging and illuminating skin care products
TIROSINASE ENZIME INHIBITION
Thyrosinase (polyphenol oxidase), a copper-containing monooxygenase, is a key enzyme involved in melanogenesis. Thyrosinase catalyzes two different reactions: the hydroxylation of tyrosine and the oxidation of the o-diphenol product, L-DOPA.
DOPA oxidation generates a highly reactive intermediate, which is oxidized to form melanin through a radical coupling pathway.
In fact, the melanocyte is subjected to a continuous oxidative stress of low degree, as melanogenesis leads to the production of hydrogen peroxide which, if improperly processed, can cause the generation of hydroxyl radicals and other reactive species of oxygen. (ROS).
The graph shows the high ability of MEDITERRANEAN WHITENING to inhibit the enzyme tyrosinase.
